Atosiban acetate yog disulfide-bonded cyclic polypeptide muaj li ntawm 9 amino acids. Nws yog ib qho oxytocin molecule hloov ntawm txoj haujlwm 1, 2, 4 thiab 8. N-terminal ntawm peptide yog 3-mercaptopropionic acid (thiol thiab sulfhydryl pawg ntawm [Cys]6 tsim ib daim ntawv cog lus disulfide), C -terminus yog nyob rau hauv daim ntawv ntawm ib tug amide, thiab lub thib ob amino acid ntawm lub N-terminus yog [D-Tyr(Et)] 2 hloov los ntawm ethylation. Atosiban acetate yog siv rau hauv cov tshuaj raws li vinegar Lub npe nrov yog atosiban acetate.
Specifications
Xim: Dawb rau Off-White
Qhov tsos: khov
Cov mis mos molecular: C43H67N11O12S2
Molar Mass 994.199 g / mol
Purity Ntau dua lossis sib npaug li 98 feem pua
Impurity Tsawg dua los yog sib npaug rau 0.5 feem pua
Daim ntawv thov
Kev sib tw antagonist ntawm cyclic peptide oxytocin receptor nyob rau hauv tsev menyuam thiab ntawm decidua thiab fetal membranes.
Vim li cas thiaj siv Atosiban?
Atosiban yog ib qho sib xyaw receptor antagonist ntawm oxytocin thiab vasopressin V1A, ib qho receptor rau oxytocin uas zoo ib yam li V1A receptor rau vasopressin. Thaum cov oxytocin receptor raug thaiv, oxytocin tseem tuaj yeem ua los ntawm V1A receptor, yog li nws yog qhov tsim nyog los thaiv cov saum toj no ob txoj kev receptor tib lub sijhawm, thiab ib qho kev tawm tsam ntawm ib tus receptor tuaj yeem cuam tshuam uterine contraction. Qhov no kuj yog ib qho ntawm cov laj thawj tseem ceeb uas yog vim li cas beta-receptor agonists, calcium ion channel blockers thiab prostaglandin synthase inhibitors tsis tuaj yeem cuam tshuam uterine contractions.
Cia
-20 degree
Cim npe nrov: Tuam Tshoj atosiban acetate manufacturers, hoobkas
